Roger and Anita meet cute through their dalmatians, Pongo and Perdita. All is wedded bliss until Anita's old college chum, Cruella DeVil, who has a psychotic obsession with fur, catches sight of Pongo and Perdita's puppies and hatches a plot to steal all the dalmatian pups she can find to make an enormous fur coat. Soon, the puppies have been dognapped and Pongo must lead a heroic cast of animals to rescue the pups before it's too late.